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Bioprocess modeling and identification
Advanced Control of Chemical Processes, Volume # 6 | Part# 1
Location: , Brazil
General Chair: Jorge Otavio Trierweiler
Program Chair: Francis J. Doyle, III.
Conference Editor: Francis J. Doyle, III.,
Jorge Otavio Trierweiler,
Argimiro R. Secchi,
Mehmet Mercangoz,
Luciane S. Ferreira
Posted online: 05-01-2008 29:23:14
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Abstract
This paper exploits a gradient-based model predictive control technique to solve an optimal switching time problem over periodic orbits. Drug delivery scheduling applications, where it is desired to maximize the averaged effect of a drug over time, motivate the study for this type of online optimization problem. The objective is to find the optimal time-switching policy between full treatment and no treatment periods. It is shown, by a numerical application to a simple drug delivery problem, that the resulting predictive algorithm drives the system to the optimal periodic orbit in the state space.
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